institutional study

Mumbai, 27th May 2024 – Intuitive, a global technology leader in minimally invasive care and the pioneer of robotic-assisted surgery today announced the findings of India’s largest collaborative and multi-institutional study on robotic-assisted partial nephrectomy (RAPN) using the da Vinci surgical system. In collaboration with 14 government and private centers across India, the study supports the use of robotic-assisted partial nephrectomy (RAPN) in surgery for renal masses. This retrospective study utilized data from 800 patient cases spanning the last 12 years, marking a significant milestone in India’s landscape for urological care.

The aim of this study, the first of its kind in India, was to validate the value and benefits of using the da Vinci surgical system in RAPN in India, providing comprehensive insights into the procedure’s efficacy and safety across diverse patient demographics and tumor complexities.

“In India, there has been a need for robust and high-quality data on robotic-assisted partial nephrectomy outcomes tailored to our population,” said Dr. Sudhir Rawal, Director, and Head of the Department of Genito Uro Oncology Services, at Rajiv Gandhi Cancer Institute and Research Centre.

“Our study results help fill this gap by providing insights into the efficacy and safety of robotic-assisted partial nephrectomy across diverse patient demographics and tumor complexities. This will help provide trained surgeons the confidence in choosing robotic-assisted surgery for renal masses, for better clinical outcomes, said Dr Rawal.”

“The results of this study are significant,” said Swati Gupta, Marketing Director at Intuitive India. “The data demonstrates the potential of the da Vinci system in improving patient outcomes for robotic-assisted partial nephrectomy in India and lays the groundwork for further advancements in robotic surgery nationwide. Collaboration with leading Indian institutions and surgeons has provided valuable insights specific to the Indian patient population. Going forward, this knowledge will be crucial in refining surgical techniques and expanding access to minimally invasive robotic surgery for more patients. We are proud to have contributed to this important research and look forward to its positive impact on patient care in India,” she added.

Key findings from the study include:

  • · Perioperative Outcomes: RAPN using da Vinci demonstrated favorable perioperative outcomes, with a median operative time of 180 minutes and a median estimated blood loss of 100 ml. The mean warm ischemia time (WIT) was 22.7 minutes, with a low conversion rate to open surgery (0.4%) and a manageable complication rate where the majority of complications were minor grade.
  • · Functional Outcomes: RAPN using da Vinci showed promising functional outcomes, with mean serum creatinine and estimated glomerular filtration rate (eGFR) levels stabilizing postoperatively. Trifecta and perfecta outcomes were achieved in 61.4% and 60% of patients, respectively, highlighting the procedure’s efficacy in preserving renal function.
  • · Comparative Analysis: The study compared favorably with international benchmarks, demonstrating comparable outcomes to previous multicentric analyses while reflecting the real-world scenario with centers of varying volumes and surgeon expertise.

“While partial nephrectomy has emerged as the preferred treatment approach for renal masses, our study supports the efficacy of using the da Vinci system in India for these procedures,” said Dr Rawal. “By establishing a comprehensive database of clinical outcomes, we aim to pave the way for further advancements in this area tailored to our population.”

The results presented in this study demonstrate strong support for an advanced technology, RAPN, establishing its safety and efficacy. This study showcases and reinforces the value and benefits of RAPN to the healthcare community at large.